解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::In previous work (Penny et al., [2005]: Neuroimage 24:350-362) we have developed a spatially regularised General Linear Model for the analysis of functional magnetic resonance imaging data that allows for the characterisation of regionally specific effects using Posterior Probability Maps (PPMs). In this paper we show...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20327
更新日期:2007-04-01 00:00:00
abstract::Carpal tunnel syndrome (CTS) is a common entrapment neuropathy of the median nerve characterized by paresthesias and pain in the first through fourth digits. We hypothesize that aberrant afferent input from CTS will lead to maladaptive cortical plasticity, which may be corrected by appropriate therapy. Functional MRI ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20261
更新日期:2007-03-01 00:00:00
abstract::Fractal dimension (FD) has been widely used to provide a quantitative description of structural complexity in the cerebral cortex. FD is an extremely compact measure of shape complexity, condensing all details into a single numeric value. We interpreted the variation of the FD in the cortical surface of normal control...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20238
更新日期:2006-12-01 00:00:00
abstract::Self-generated sensory stimulation can be distinguished from externally generated stimulation that is otherwise identical. To determine how the brain differentiates external from self-generated noxious stimulation and which structures of the lateral pain system use neural signals to predict the sensory consequences of...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20217
更新日期:2006-09-01 00:00:00
abstract::We used emotional expectancy to study attentional modulation in the processing of emotional stimuli. During functional magnetic resonance imaging (fMRI), volunteers saw emotional and neutral expectancy cues signaling the subsequent presentation of corresponding emotional or neutral pictorial stimuli. As a control, emo...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20209
更新日期:2006-08-01 00:00:00
abstract::It is becoming common to collect data from multiple functional magnetic resonance imaging (fMRI) paradigms on a single individual. The data from these experiments are typically analyzed separately and sometimes directly subtracted from one another on a voxel-by-voxel basis. These comparative approaches, although usefu...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20204
更新日期:2006-07-01 00:00:00
abstract::Simultaneous electroencephalogram/functional magnetic resonance imaging (EEG-fMRI) during interictal epileptiform discharges can result in positive (activation) and negative (deactivation) changes in the blood oxygenation level-dependent (BOLD) signal. Activation probably reflects increased neuronal activity and energ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20193
更新日期:2006-06-01 00:00:00
abstract::Functional magnetic resonance imaging (fMRI) and positron emission tomography (PET) were used to map brain activation during language tasks. While previous studies have compared performance between alphabetic literate and illiterate subjects, there have been no such data in Chinese-speaking individuals. In this study,...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20173
更新日期:2006-02-01 00:00:00
abstract::We present a new technique for segmentation of skull and scalp in T(1)-weighted magnetic resonance images (MRIs) of the human head. Our method uses mathematical morphological operations to generate realistic models of the skull, scalp, and brain that are suitable for electroencephalography (EEG) and magnetoencephalogr...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20159
更新日期:2005-12-01 00:00:00
abstract::The relationship between neocortical structure and function is a key area of research in neuroscience. Most studies of neural function, whether using neurophysiology or neuroimaging methods, are interpreted with relation to the underlying cortical myelo- and cytoarchitecture. For functional neuroimaging studies this o...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20162
更新日期:2005-12-01 00:00:00
abstract::Human behavior reflects a continual negotiation of automatic and directed actions. The oculomotor network is a well-characterized neural system in which to study this balance of behavioral control. For instance, saccades made toward and away from a flashed visual stimulus (prosaccades and antisaccades, respectively) a...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20146
更新日期:2005-10-01 00:00:00
abstract::Our primary question was to learn whether mentally composing drawings of their own choice produce different brain electric features in artists and laymen. To this purpose, we studied multichannel electroencephalograph (EEG) signals from two broad groups (all participants were females): artists (professionally trained ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20104
更新日期:2005-09-01 00:00:00
abstract::Previous studies exploring the neural substrates of executive functioning used task-specific analyses, which might not be the most appropriate approach due to the difficulty of precisely isolating executive functions. Consequently, the aim of this study was to use positron emission tomography (PET) to reexamine by con...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20118
更新日期:2005-08-01 00:00:00
abstract::Despite the clinical significance of event-related potential (ERP) latency abnormalities, little attention has focused on the anatomic substrate of latency variability. Volume conduction models do not identify the anatomy responsible for delayed neural transmission between neural sources. To explore the anatomic subst...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20103
更新日期:2005-07-01 00:00:00
abstract::Standard procedures to achieve quality assessment (QA) of functional magnetic resonance imaging (fMRI) data are of great importance. A standardized and fully automated procedure for QA is presented that allows for classification of data quality and the detection of artifacts by inspecting temporal variations. The appl...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20096
更新日期:2005-06-01 00:00:00
abstract::Coordinate-based, voxel-wise meta-analysis is an exciting recent addition to the human functional brain mapping literature. In view of the critical importance of selection criteria for any valid meta-analysis, a taxonomy of experimental design should be an important tool for aiding in the design of rigorous meta-analy...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20141
更新日期:2005-05-01 00:00:00
abstract::The neural systems sustaining object naming were examined using the activation likelihood estimation (ALE) meta-analysis approach on the results of 16 previously published studies. The activation task in each study required subjects to name pictures of objects or animals, but the baseline tasks varied. Separate meta-a...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20132
更新日期:2005-05-01 00:00:00
abstract::There are several types of experiment in which it is useful to have subjects speak overtly in a magnetic resonance imaging (MRI) scanner, including those studying the articulatory apparatus and the neural basis of speech production, and fMRI experiments in which speech is used as a response modality. Although it is re...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20085
更新日期:2005-04-01 00:00:00
abstract::Individuals with a constitutional chromosome abnormality consisting of a deletion of a portion of the long arm of chromosome 18 (18q-) have a high incidence ( approximately 95%) of dysmyelination. Neuroradiologic findings in affected children report a smaller corpus callosum, but this finding has not been quantified. ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20090
更新日期:2005-04-01 00:00:00
abstract::Differences in brain activity of children with attention deficit hyperactivity disorder (ADHD) have been compared to normal healthy controls, suggesting neural correlates of cognitive/behavioral symptoms. Symptoms are improved with methylphenidate treatment but limited sources can be cited to show how brain activity i...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20067
更新日期:2005-03-01 00:00:00
abstract::We describe a system that localizes a single dipole to reasonable accuracy from noisy magnetoencephalographic (MEG) measurements in real time. At its core is a multilayer perceptron (MLP) trained to map sensor signals and head position to dipole location. Including head position overcomes the previous need to retrain ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20068
更新日期:2005-01-01 00:00:00
abstract::Human brain mapping allows the systematic assessment of interindividual differences in functional brain anatomy. Functional transcranial Doppler sonography (fTCD) is an imaging tool that allows for fast and mobile assessment of hemispheric lateralization of task-related brain activation. It is ideal to screen large co...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20055
更新日期:2004-11-01 00:00:00
abstract::The spatial organization of nonlinear interactions between different brain regions during the first NREM sleep stage is investigated. This is achieved via consideration of four bipolar electrode derivations, Fp1F3, Fp2F4, O1P3, O2P4, which are used to compare anterior and posterior interhemispheric interactions and le...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20052
更新日期:2004-10-01 00:00:00
abstract::Human albinism is characterized by a disturbance of the chiasmatic projection system leading to predominant representation of just one eye in the contralateral hemisphere. Patients show congenital nystagmus without perceiving oscillopsia. The purpose of the present study was to demonstrate the consequences of atypical...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20046
更新日期:2004-09-01 00:00:00
abstract::We investigated neural substrates of global/local processing of bilateral hierarchical stimuli using functional magnetic resonance imaging (fMRI). Subjects were presented with two compound letters that were displayed simultaneously in the left and right visual fields, respectively. In a steady-state, block-design para...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20044
更新日期:2004-08-01 00:00:00
abstract::It is assumed widely that the clinical expression of Parkinson's Disease (PD), both motor and cognitive, is subtended by topographically distributed brain networks. However, little is known about the functional neuroanatomy of executive dysfunction in PD. Our objective was to validate further in a PD group the use of ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20033
更新日期:2004-07-01 00:00:00
abstract::During the developmental stage, the brain undergoes anatomic, functional, and metabolic changes necessary to support the complex adaptive behavior of a mature individual. Estimation of developmental changes occurring in different regions of the brain would provide a means of relating various behavioral phenomena to ma...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20020
更新日期:2004-06-01 00:00:00
abstract::We contend that powerful group studies can be conducted using magnetoencephalography (MEG), which can provide useful insights into the approximate distribution of the neural activity detected with MEG without requiring magnetic resonance imaging (MRI) for each participant. Instead, a participant's MRI is approximated ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10133
更新日期:2003-11-01 00:00:00
abstract::Landau-Kleffner syndrome (LKS) is a rare acquired aphasia occurring in otherwise healthy children, together with spike-wave discharges predominating over superior temporal regions and activated by sleep. Although the outcome of language abilities is variable, a residual impairment in verbal short-term memory (STM) is ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10113
更新日期:2003-07-01 00:00:00
abstract::In BOLD fMRI data analysis, robust and accurate estimation of the Hemodynamic Response Function (HRF) is still under investigation. Parametric methods assume the shape of the HRF to be known and constant throughout the brain, whereas non-parametric methods mostly rely on artificially increasing the signal-to-noise rat...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10100
更新日期:2003-05-01 00:00:00
abstract::The neural basis of the automatic activation of words was investigated in an fMRI study. In the study, words were presented briefly (51 or 151 msec) followed by a mask. To prevent attentional processing, subjects attended to the masks and not the words, and were required to make perceptual judgment about the masks. We...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10096
更新日期:2003-03-01 00:00:00
abstract::A new procedure to model extended cortical sources from EEG and MEG recordings based on a probabilistic approach is presented. The method (SPMECS) was implemented within the framework of maximum likelihood estimators. Neuronal activity generating EEG or MEG signals was characterized by the number of sources and their ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10079
更新日期:2003-02-01 00:00:00
abstract::Functional imaging studies consistently find that emotional stimuli activate the posterior cingulate cortex, a region that appears to have memory-related functions. However, prior imaging studies have not controlled for non-emotional stimulus features that might activate this region by engaging memory processes unrela...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10075
更新日期:2003-01-01 00:00:00
abstract::The applicability of functional magnetic resonance imaging (fMRI) in patients with Alzheimer's disease (AD) or schizophrenia is frequently limited by cognitive impairment, which prevents the adequate execution of complex tasks. An experimental design that puts only minor demands on the patients' cognitive ability but ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10071
更新日期:2002-12-01 00:00:00
abstract::We describe a method for the statistical parametric mapping of low resolution electromagnetic tomography (LORETA) using high-density electroencephalography (EEG) and individual magnetic resonance images (MRI) to investigate the characteristics of the mismatch negativity (MMN) generators in schizophrenia. LORETA, using...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10059
更新日期:2002-11-01 00:00:00
abstract::We performed an fMRI one-back recognition study aimed at distinguishing the semantic versus perceptual aspects of how objects and their written forms are processed. There were three types of visually presented items: pictures (schematic drawings of objects); words identifying these objects; and a mixed condition in wh...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10037
更新日期:2002-07-01 00:00:00
abstract::Humans take a long time to respond to the slow visual motion of an object. It is not known what neural mechanism causes this delay. We measured magnetoencephalographic neural responses to light spot motion onset within a wide speed range (0.4-500 degrees /sec) and compared these with human reaction times (RTs). The me...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10033
更新日期:2002-06-01 00:00:00
abstract::Our objective was to develop a diffusion tensor MR imaging pulse sequence that allows whole brain coverage with isotropic resolution within a clinically acceptable time. A single-shot, cardiac-gated MR pulse sequence, optimized for measuring the diffusion tensor in human brain, was developed to provide whole-brain cov...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10018
更新日期:2002-04-01 00:00:00
abstract::We monitored regional cerebral activity with BOLD fMRI while subjects were presented written sentences differing in their grammatical structure (subject-relative or object-relative center-embedded clauses) and their short-term memory demands (short or long antecedent-gap linkages). A core region of left posterior supe...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10006
更新日期:2002-02-01 00:00:00
abstract::Independent component analysis (ICA) has been shown as a promising tool for the analysis of functional magnetic resonance imaging (fMRI) time series. Each of these studies, however, used a general-purpose algorithm for performing ICA and the computational efficiency and accuracy of elicited neuronal activations have n...
journal_title:Human brain mapping
pub_type: 临床试验,杂志文章
doi:10.1002/hbm.1061
更新日期:2002-01-01 00:00:00